Study links neurotypical brain organization to genes linked to autism and schizophrenia

Study links neurotypical brain organization to genes linked to autism and schizophrenia

Three patterns of gene expression are each consistent with unique features of known neurobiology: C1 is consistent with functional connection strength, C2 is consistent with brain oscillations in the theta …

Read more

Study shows two copies of the APOE4 gene are behind up to 20% of Alzheimer’s cases

Study shows two copies of the APOE4 gene are behind up to 20% of Alzheimer's cases

Penetrance and predictive value of APOE4 homozygosity in AD. a, Distribution of ADNC scores by age at death. b, Frequency of amyloid and tau biomarker positivity within 5-year age intervals. …

Read more

Genetic variant common among black Americans contributes to huge cardiovascular disease burden, researchers show

Genetic variant common among black Americans contributes to huge cardiovascular disease burden, researchers show

Image source: Image generated by artificial intelligence Researchers from Brigham and Women’s Hospital and Duke University show that 3-4% of self-identified black people in the United States have a genetic …

Read more

Study finds genetic link between adolescent growth and long-term health

Study finds genetic link between adolescent growth and long-term health

Average peak height velocity (cm/year) and average age at peak height velocity (years) for groups with different ancestral backgrounds. The yellow and purple lines represent the linear model fit to …

Read more

Research team identifies four new genetic risk factors for multiple system atrophy

Research team identifies four new genetic risk factors for multiple system atrophy

Credit: Neurons (2024). DOI: 10.1016/j.neuron.2024.04.002 In a study published in Neurons, researchers have discovered four new genetic risk factors for multiple system atrophy (MSA), shedding light on this poorly understood …

Read more

Study stratifies risk of dilated cardiomyopathy in asymptomatic genetic carriers for first time

Study stratifies risk of dilated cardiomyopathy in asymptomatic genetic carriers for first time

MRI of the heart in a patient with dilated cardiomyopathy (left) and in a patient without heart disease (right). People with dilated cardiomyopathy have an enlarged heart with a reduced …

Read more

A new strategy for assessing the natural history of leukodystrophies

A new strategy for assessing the natural history of leukodystrophies

Image source: Unsplash/CC0 Public Domain Natural history studies are an important standard in medical research because they analyze demographic, genetic, environmental, and other variables to better understand how diseases develop …

Read more

Experts review current status of retinoblastoma research

Experts review current status of retinoblastoma research

Image source: Pixabay/CC0 Public Domain Retinoblastoma is a rare pediatric cancer with approximately 250,300 new cases in the United States and 8,000 worldwide each year. This cancer grows in the …

Read more

New treatment shows promise in hard-to-treat pediatric cancer

New treatment shows promise in hard-to-treat pediatric cancer

Diana Azzam, a researcher in Azzam’s lab at Florida International University, and her clinical study participant Logan Jenner.Image source: Florida International University Researchers have developed a functional precision medicine approach …

Read more

Scientists discover 95 genomic regions linked to PTSD

Scientists discover 95 genomic regions linked to PTSD

Image source: Unsplash/CC0 Public Domain In post-traumatic stress disorder (PTSD), intrusive thoughts, mood changes, and other symptoms following a trauma can greatly affect a person’s quality of life. About 6 …

Read more